Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts

BACKGROUND: Tumor hypoxia is associated with resistance to radiotherapy and chemotherapy. In head and neck squamous cell carcinoma (HNSCC), nimorazole, an oxygen mimic, combined with radiotherapy (RT) enabled to improve loco-regional control (LRC) in some patients with hypoxic tumors but it is unkno...

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Detalles Bibliográficos
Autores principales: Koi, Lydia, Bitto, Verena, Weise, Corina, Möbius, Lisa, Linge, Annett, Löck, Steffen, Yaromina, Ala, Besso, María José, Valentini, Chiara, Pfeifer, Manuel, Overgaard, Jens, Zips, Daniel, Kurth, Ina, Krause, Mechthild, Baumann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464469/
https://www.ncbi.nlm.nih.gov/pubmed/37633930
http://dx.doi.org/10.1186/s12967-023-04439-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464469/
https://www.ncbi.nlm.nih.gov/pubmed/37633930
http://dx.doi.org/10.1186/s12967-023-04439-2

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