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RING box protein-1(RBX1), a key component of SCF E3 ligase, induced multiple myeloma cell drug-resistance though suppressing p27

Multiple myeloma (MM) is a clonal disease of plasma cells that remains, for the most part, incurable despite the advent of several novel therapeutics. The elevated expression of p27 and its association with cell-cycle arrest is speculated to be one of the major mechanisms by which MM cells escape th...

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Detalles Bibliográficos
Autores principales: Bao, Enfang, Zhou, Yu, He, Song, Tang, Jie, He, Yunhua, Zhu, Mengyuan, Cheng, Chun, Wang, Yuchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464534/
https://www.ncbi.nlm.nih.gov/pubmed/37639640
http://dx.doi.org/10.1080/15384047.2023.2231670