Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2

Ribosomal RNAs are decorated by numerous post-transcriptional modifications whose exact roles in ribosome biogenesis, function, and human pathophysiology remain largely unknown. Here, we report a targeted direct rRNA sequencing approach involving a substrate selection step and demonstrate its suitab...

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Detalles Bibliográficos
Autores principales: Naarmann-de Vries, Isabel S., Zorbas, Christiane, Lemsara, Amina, Piechotta, Michael, Ernst, Felix G. M., Wacheul, Ludivine, Lafontaine, Denis L. J., Dieterich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Technical Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464549/
https://www.ncbi.nlm.nih.gov/pubmed/37635368
http://dx.doi.org/10.1080/15476286.2023.2248752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464549/
https://www.ncbi.nlm.nih.gov/pubmed/37635368
http://dx.doi.org/10.1080/15476286.2023.2248752

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