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Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2
Ribosomal RNAs are decorated by numerous post-transcriptional modifications whose exact roles in ribosome biogenesis, function, and human pathophysiology remain largely unknown. Here, we report a targeted direct rRNA sequencing approach involving a substrate selection step and demonstrate its suitab...
Autores principales: | Naarmann-de Vries, Isabel S., Zorbas, Christiane, Lemsara, Amina, Piechotta, Michael, Ernst, Felix G. M., Wacheul, Ludivine, Lafontaine, Denis L. J., Dieterich, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464549/ https://www.ncbi.nlm.nih.gov/pubmed/37635368 http://dx.doi.org/10.1080/15476286.2023.2248752 |
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