Cargando…

Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell

Recent studies have demonstrated that the antitumor immunity of immune cells can be modulated by gut microbiota and their metabolites. However, the underlying mechanisms remain unclear. Here, we showed that the serum butyric acid level is positively correlated with the expression of programmed cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xinhai, Li, Ke, Liu, Guichao, Wu, Ruan, Zhang, Yan, Wang, Siying, Xu, Meng, Lu, Ligong, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464552/
https://www.ncbi.nlm.nih.gov/pubmed/37635362
http://dx.doi.org/10.1080/19490976.2023.2249143