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The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication

Non-structural protein 5 (Nsp5) is a cysteine protease that plays a key role in SARS-CoV-2 replication, suppressing host protein synthesis and promoting immune evasion. The investigation of natural products as a potential strategy for Nsp5 inhibition is gaining attention as a means of developing ant...

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Detalles Bibliográficos
Autores principales: Bianconi, Elisa, Gidari, Anna, Souma, Maria, Sabbatini, Samuele, Grifagni, Deborah, Bigiotti, Carlo, Schiaroli, Elisabetta, Comez, Lucia, Paciaroni, Alessandro, Cantini, Francesca, Francisci, Daniela, Macchiarulo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464554/
https://www.ncbi.nlm.nih.gov/pubmed/37638806
http://dx.doi.org/10.1080/14756366.2023.2251721