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The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication
Non-structural protein 5 (Nsp5) is a cysteine protease that plays a key role in SARS-CoV-2 replication, suppressing host protein synthesis and promoting immune evasion. The investigation of natural products as a potential strategy for Nsp5 inhibition is gaining attention as a means of developing ant...
Autores principales: | Bianconi, Elisa, Gidari, Anna, Souma, Maria, Sabbatini, Samuele, Grifagni, Deborah, Bigiotti, Carlo, Schiaroli, Elisabetta, Comez, Lucia, Paciaroni, Alessandro, Cantini, Francesca, Francisci, Daniela, Macchiarulo, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464554/ https://www.ncbi.nlm.nih.gov/pubmed/37638806 http://dx.doi.org/10.1080/14756366.2023.2251721 |
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