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Assessment of the proarrhythmic effects of repurposed antimalarials for COVID-19 treatment using a comprehensive in vitro proarrhythmia assay (CiPA)

Due to the outbreak of the SARS-CoV-2 virus, drug repurposing and Emergency Use Authorization have been proposed to treat the coronavirus disease 2019 (COVID-19) during the pandemic. While the efficiency of the drugs has been discussed, it was identified that certain compounds, such as chloroquine a...

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Detalles Bibliográficos
Autores principales: Yoon, Seung-Hyun, Lee, Hyun-Lee, Jeong, Da Un, Lim, Ki Moo, Park, Seong-Jun, Kim, Ki-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464612/
https://www.ncbi.nlm.nih.gov/pubmed/37649890
http://dx.doi.org/10.3389/fphar.2023.1220796