Complex I deficiency in m.3243A>G fibroblasts is alleviated by reducing NADH accumulation

Introduction: Mitochondrial disease is a spectrum of debilitating disorders caused by mutations in the mitochondrial DNA (mtDNA) or nuclear DNA that compromises the respiratory chain. Mitochondrial 3243A>G (m.3243 A>G) is the most common mutation showing great heterogeneity in phenotype. Previ...

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Detalles Bibliográficos
Autores principales: Liufu, Tongling, Yu, Haiyan, Yu, Jiaxi, Yu, Meng, Tian, Yue, Ou, Yichun, Deng, Jianwen, Xing, Guogang, Wang, Zhaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464909/
https://www.ncbi.nlm.nih.gov/pubmed/37650111
http://dx.doi.org/10.3389/fphys.2023.1164287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464909/
https://www.ncbi.nlm.nih.gov/pubmed/37650111
http://dx.doi.org/10.3389/fphys.2023.1164287

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