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DNA methylation cooperates with H3K9me2 at HCN4 promoter to regulate the differentiation of bone marrow mesenchymal stem cells into pacemaker-like cells

Sick sinus syndrome (SSS) is a a life-threatening disease, and biological pacemakers derived from bone marrow mesenchymal stem cells (BMSCs) have practical clinical applications. Previous studies demonstrated that epigenetics plays an important role in the differentiation of BMSCs into pacemaker-lik...

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Detalles Bibliográficos
Autores principales: Sun, XiaoLin, Jin, Kai, Ding, Xiangwei, Ruan, Zhongbao, Xu, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464974/
https://www.ncbi.nlm.nih.gov/pubmed/37643180
http://dx.doi.org/10.1371/journal.pone.0289510