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Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila
Miro GTPases control mitochondrial morphology, calcium homeostasis, and regulate mitochondrial distribution by mediating their attachment to the kinesin and dynein motor complex. It is not clear, however, how Miro proteins spatially and temporally integrate their function as acute disruption of prot...
Autores principales: | Mattedi, Francesca, Lloyd-Morris, Ethlyn, Hirth, Frank, Vagnoni, Alessio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465005/ https://www.ncbi.nlm.nih.gov/pubmed/37590319 http://dx.doi.org/10.1371/journal.pbio.3002273 |
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