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Long-term combination therapy with Metformin and Oxymetholone in a Fanconi Anemia mouse model

Fanconi Anemia (FA) is a disease caused by defective DNA repair which manifests as bone marrow failure, cancer predisposition, and developmental defects. Mice containing inactivating mutations in one or more genes in the FA pathway partially mimic the human disease. We previously reported that monot...

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Detalles Bibliográficos
Autores principales: Dorrell, Craig, Peters, Alexander M, Zhang, Qingshuo, Balaji, Niveditha, Baradar, Kevin, Mochizuki-Kashio, Makiko, Major, Angela, Finegold, Milton, Liu, Chih-Wei, Lu, Kun, Grompe, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465065/
https://www.ncbi.nlm.nih.gov/pubmed/37649908
http://dx.doi.org/10.1101/2023.08.16.553572