Secretome of senescent hepatic stellate cells favors malignant transformation from nonalcoholic steatohepatitis-fibrotic progression to hepatocellular carcinoma

Background: Hepatic fibrosis is a premalignant lesion, and how injured hepatocytes transform into malignancy in a fibrotic microenvironment is poorly understood. Senescence is one of major fates of activated hepatic stellate cells (HSCs). Paucity of literature is available regarding the influence of...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Zhang, Li, Ma, Yue, Xie, Li, Yang, Yong-yu, Jin, Cheng, Chen, Hui, Zhou, Ying, Song, Guang-qi, Ding, Jia, Wu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465212/
https://www.ncbi.nlm.nih.gov/pubmed/37649614
http://dx.doi.org/10.7150/thno.85369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465212/
https://www.ncbi.nlm.nih.gov/pubmed/37649614
http://dx.doi.org/10.7150/thno.85369

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