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TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy

Background: Cisplatin is a widely used anti-tumor agent but its use is frequently limited by nephrotoxicity. Transient receptor potential melastatin 2 (TRPM2) is a non-selective cation channel which is generally viewed as a sensor of oxidative stress, and increasing evidence supports its link with a...

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Detalles Bibliográficos
Autores principales: Yu, Binfeng, Jin, Lini, Yao, Xi, Zhang, Yi, Zhang, Gensheng, Wang, Fangqin, Su, Xinwan, Fang, Qiuyuan, Xiao, Liang, Yang, Yi, Jiang, Lin-Hua, Chen, Jianghua, Yang, Wei, Lin, Weiqiang, Han, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465213/
https://www.ncbi.nlm.nih.gov/pubmed/37649595
http://dx.doi.org/10.7150/thno.84655