DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis

Background: Increasing evidence suggests that hemodynamic disturbed flow induces endothelial dysfunction via a complex biological process so-called endothelial to mesenchymal transition (EndoMT). Recently, DNA methyltransferases (DNMTs) was reported as a key molecular mediator to promote EndoMT. Our...

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Detalles Bibliográficos
Autores principales: Zhao, Jianan, Zhao, Chuanrong, Yang, Fangfang, Jiang, Zhitong, Zhu, Juanjuan, Yao, Weijuan, Pang, Wei, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465216/
https://www.ncbi.nlm.nih.gov/pubmed/37649604
http://dx.doi.org/10.7150/thno.84427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465216/
https://www.ncbi.nlm.nih.gov/pubmed/37649604
http://dx.doi.org/10.7150/thno.84427

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