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DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis
Background: Increasing evidence suggests that hemodynamic disturbed flow induces endothelial dysfunction via a complex biological process so-called endothelial to mesenchymal transition (EndoMT). Recently, DNA methyltransferases (DNMTs) was reported as a key molecular mediator to promote EndoMT. Our...
Autores principales: | Zhao, Jianan, Zhao, Chuanrong, Yang, Fangfang, Jiang, Zhitong, Zhu, Juanjuan, Yao, Weijuan, Pang, Wei, Zhou, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465216/ https://www.ncbi.nlm.nih.gov/pubmed/37649604 http://dx.doi.org/10.7150/thno.84427 |
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