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The spatial coexistence of TIGIT/CD155 defines poorer survival and resistance to adjuvant chemotherapy in pancreatic ductal adenocarcinoma

Background: Targeting emerging T cell immunoreceptor with immunoglobulin and ITIM domain (TIGIT)/CD155 axis shows promise for restoring anti-tumor immunity, but its immune phenotypes and prognostic significance in a large cohort of pancreatic ductal adenocarcinoma (PDAC) are limited. Methods: Three...

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Detalles Bibliográficos
Autores principales: Ma, Heng, Chen, Xianlong, Mo, Shengwei, Mao, Xinxin, Chen, Jingci, Liu, Yilin, Lu, Zhaohui, Yu, Shuangni, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465224/
https://www.ncbi.nlm.nih.gov/pubmed/37649613
http://dx.doi.org/10.7150/thno.86547