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Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis

Background: Peritoneal dialysis (PD) is limited by gradual fibrotic remodeling in the peritoneum, a process involving profibrotic response of mesothelial cells. However, the role of fatty acid oxidation (FAO) and carnitine palmitoyltransferase 1A (CPT1A) in this process remains unexplored. Methods:...

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Detalles Bibliográficos
Autores principales: Su, Wenyan, Hu, Zuoyu, Zhong, Xiaohong, Cong, Ansheng, Zhang, Ying, Zhou, Zhanmei, Li, Jianyi, Su, Cailing, Huang, Yujie, Cao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465225/
https://www.ncbi.nlm.nih.gov/pubmed/37649600
http://dx.doi.org/10.7150/thno.84921