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Parathyroid Hormone-Related Protein Promotes the Proliferation of Patient-Derived Glioblastoma Stem Cells via Activating cAMP/PKA Signaling Pathway

BACKGROUND AND OBJECTIVES: Glioblastoma (GBM) is an aggressive primary brain tumor characterized by its heterogeneity and high recurrence and lethality rates. Glioblastoma stem cells (GSCs) play a crucial role in therapy resistance and tumor recurrence. Therefore, targeting GSCs is a key objective i...

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Detalles Bibliográficos
Autores principales: Guo, Zhenyu, Huang, Tingqin, Liu, Yingfei, Liu, Chongxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465338/
https://www.ncbi.nlm.nih.gov/pubmed/37385633
http://dx.doi.org/10.15283/ijsc22097