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Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates

Mycobacteriophages show promise as therapeutic agents for non-tuberculous mycobacterium infections. However, little is known about phage recognition of Mycobacterium cell surfaces or mechanisms of phage resistance. We show here that trehalose polyphleates (TPPs)—high-molecular-weight, surface-expose...

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Detalles Bibliográficos
Autores principales: Wetzel, Katherine S., Illouz, Morgane, Abad, Lawrence, Aull, Haley G., Russell, Daniel A., Garlena, Rebecca A., Cristinziano, Madison, Malmsheimer, Silke, Chalut, Christian, Hatfull, Graham F., Kremer, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465359/
https://www.ncbi.nlm.nih.gov/pubmed/37644325
http://dx.doi.org/10.1038/s41564-023-01451-6