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Targeting MerTK decreases efferocytosis and increases anti-tumor immune infiltrate in prostate cancer

The prostate cancer tumor microenvironment (TME) is comprised of many cell types that can contribute to and influence tumor progression. Some of the most abundant prostate cancer TME cells are macrophages, which can be modeled on a continuous spectrum of M1-like (anti-tumor macrophages) to M2-like (...

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Detalles Bibliográficos
Autores principales: Myers Chen, Kayla V., de Groot, Amber E., Mendez, Sabrina A., Mallin, Mikaela M., Amend, Sarah R., Pienta, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465384/
https://www.ncbi.nlm.nih.gov/pubmed/37644281
http://dx.doi.org/10.1007/s12032-023-02153-z