WDR62-deficiency Causes Autism-like Behaviors Independent of Microcephaly in Mice

Brain size abnormality is correlated with an increased frequency of autism spectrum disorder (ASD) in offspring. Genetic analysis indicates that heterozygous mutations of the WD repeat domain 62 (WDR62) are associated with ASD. However, biological evidence is still lacking. Our study showed that Wdr...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Dan, Zhi, Yiqiang, Liu, Xinyi, Guan, Le, Yu, Jurui, Zhang, Dan, Zhang, Weiya, Wang, Yaqing, Tao, Wucheng, Xu, Zhiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465473/
https://www.ncbi.nlm.nih.gov/pubmed/36571716
http://dx.doi.org/10.1007/s12264-022-00997-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465473/
https://www.ncbi.nlm.nih.gov/pubmed/36571716
http://dx.doi.org/10.1007/s12264-022-00997-5

Ejemplares similares