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γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection

African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in a murine model of infection using spatial and single cell transcriptomics. We detect expan...

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Detalles Bibliográficos
Autores principales: Quintana, Juan F., Sinton, Matthew C., Chandrasegaran, Praveena, Lestari, Agatha Nabilla, Heslop, Rhiannon, Cheaib, Bachar, Ogunsola, John, Ngoyi, Dieudonne Mumba, Kuispond Swar, Nono-Raymond, Cooper, Anneli, Mabbott, Neil A., Coffelt, Seth B., MacLeod, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465518/
https://www.ncbi.nlm.nih.gov/pubmed/37644007
http://dx.doi.org/10.1038/s41467-023-40962-y