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γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in a murine model of infection using spatial and single cell transcriptomics. We detect expan...
Autores principales: | Quintana, Juan F., Sinton, Matthew C., Chandrasegaran, Praveena, Lestari, Agatha Nabilla, Heslop, Rhiannon, Cheaib, Bachar, Ogunsola, John, Ngoyi, Dieudonne Mumba, Kuispond Swar, Nono-Raymond, Cooper, Anneli, Mabbott, Neil A., Coffelt, Seth B., MacLeod, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465518/ https://www.ncbi.nlm.nih.gov/pubmed/37644007 http://dx.doi.org/10.1038/s41467-023-40962-y |
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