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A portable regulatory RNA array design enables tunable and complex regulation across diverse bacteria

A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. Toward addressing this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a design strategy to achieve tunable gene control. First, we demons...

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Detalles Bibliográficos
Autores principales: Liu, Baiyang, Samaniego, Christian Cuba, Bennett, Matthew R., Franco, Elisa, Chappell, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465534/
https://www.ncbi.nlm.nih.gov/pubmed/37644054
http://dx.doi.org/10.1038/s41467-023-40785-x