Improving quantitation accuracy in isobaric-labeling mass spectrometry experiments with spectral library searching and feature-based peptide-spectrum match filter

Isobaric labeling relative quantitation is one of the dominating proteomic quantitation technologies. Traditional quantitation pipelines for isobaric-labeled mass spectrometry data are based on sequence database searching. In this study, we present a novel quantitation pipeline that integrates seque...

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Detalles Bibliográficos
Autores principales: Kuo, Tzu-Yun, Wang, Jen-Hung, Huang, Yung-Wen, Sung, Ting-Yi, Chen, Ching-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465558/
https://www.ncbi.nlm.nih.gov/pubmed/37644119
http://dx.doi.org/10.1038/s41598-023-41124-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465558/
https://www.ncbi.nlm.nih.gov/pubmed/37644119
http://dx.doi.org/10.1038/s41598-023-41124-2

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