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Mycobacterial DNA-binding protein 1 is critical for BCG survival in stressful environments and simultaneously regulates gene expression

Survival of the live attenuated Bacillus Calmette-Guérin (BCG) vaccine amidst harsh host environments is key for BCG effectiveness as it allows continuous immune response induction and protection against tuberculosis. Mycobacterial DNA binding protein 1 (MDP1), a nucleoid associated protein, is esse...

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Detalles Bibliográficos
Autores principales: Shaban, Amina K., Gebretsadik, Gebremichal, Hakamata, Mariko, Takihara, Hayato, Inouchi, Erina, Nishiyama, Akihito, Ozeki, Yuriko, Tateishi, Yoshitaka, Nishiuchi, Yukiko, Yamaguchi, Takehiro, Ohara, Naoya, Okuda, Shujiro, Matsumoto, Sohkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465568/
https://www.ncbi.nlm.nih.gov/pubmed/37644087
http://dx.doi.org/10.1038/s41598-023-40941-9