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Development of the novel GlyT1 inhibitor, iclepertin (BI 425809), for the treatment of cognitive impairment associated with schizophrenia

Schizophrenia is a psychiatric disorder characterised by symptoms in three domains: positive (e.g. delusions, hallucinations), negative (e.g. social withdrawal, lack of motivation) and cognitive (e.g. working memory and executive function impairment). Cognitive impairment associated with schizophren...

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Detalles Bibliográficos
Autores principales: Rosenbrock, Holger, Desch, Michael, Wunderlich, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465677/
https://www.ncbi.nlm.nih.gov/pubmed/36971864
http://dx.doi.org/10.1007/s00406-023-01576-z