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Antitumor effect of anti-vascular therapy with STING agonist depends on the tumor microenvironment context

INTRODUCTION: Targeting tumor vasculature is an efficient weapon to fight against cancer; however, activation of alternative pathways to rebuild the disrupted vasculature leads to rapid tumor regrowth. Immunotherapy that exploits host immune cells to elicit and sustain potent antitumor response has...

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Detalles Bibliográficos
Autores principales: Czapla, Justyna, Drzyzga, Alina, Matuszczak, Sybilla, Cichoń, Tomasz, Rusin, Marek, Jarosz-Biej, Magdalena, Pilny, Ewelina, Smolarczyk, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465696/
https://www.ncbi.nlm.nih.gov/pubmed/37655095
http://dx.doi.org/10.3389/fonc.2023.1249524