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Molecular determinants of etoposide resistance in HL60 cells

Chemotherapy resistance is the main reason for treatment failure in acute myeloid leukemia (AML) and the major cause of its mortality. Etoposide is a DNA topoisomerase-II inhibitor that is used either as a single agent or in combination with cytarabine, azacytidine, vinca alkaloids, and anthracyclin...

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Detalles Bibliográficos
Autores principales: Alghamdi, Rasha H, Ahmed, Farid, Ibrahim, Sara M, Pushparaj, Peter N, Schulten, Hans Jurgen, Abuzenadah, Adel M, Almalki, Abdulrahman L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465782/
https://www.ncbi.nlm.nih.gov/pubmed/37654838
http://dx.doi.org/10.6026/97320630018894