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Antibacterial activity of the novel oxazolidinone contezolid (MRX-I) against Mycobacterium abscessus

OBJECTIVE: To evaluate contezolid (MRX-I) antibacterial activity against Mycobacterium abscessus in vitro and in vivo and to assess whether MRX-I treatment can prolong survival of infected zebrafish. METHODS: MRX-I inhibitory activity against M. abscessus in vitro was assessed by injecting MRX-I int...

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Detalles Bibliográficos
Autores principales: Gao, Shan., Nie, Wenjuan., Liu, Lina., Su, Lei., You, Yingxia., Geng, Ruixue., Chu, Naihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465794/
https://www.ncbi.nlm.nih.gov/pubmed/37655300
http://dx.doi.org/10.3389/fcimb.2023.1225341