Insertion of an immunodominant T helper cell epitope within the Group A Streptococcus M protein promotes an IFN-γ-dependent shift from a non-protective to a protective immune response

The common pathogen Group A Streptococcus (GAS, Streptococcus pyogenes) is an extracellular bacterium that is associated with a multitude of infectious syndromes spanning a wide range of severity. The surface-exposed M protein is a major GAS virulence factor that is also target for protective antibo...

Descripción completa

Detalles Bibliográficos
Autores principales: Emami, Shiva, Rojas Converso, Thiago, Persson, Jenny J., Johansson-Lindbom, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465795/
https://www.ncbi.nlm.nih.gov/pubmed/37654501
http://dx.doi.org/10.3389/fimmu.2023.1241485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465795/
https://www.ncbi.nlm.nih.gov/pubmed/37654501
http://dx.doi.org/10.3389/fimmu.2023.1241485

Ejemplares similares