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FG-4592 relieves diabetic kidney disease severity by influencing metabolic profiles via gut microbiota reconstruction in both human and mouse models

Objective: Diabetic kidney disease (DKD) is one of the most prevalent complications of diabetes mellitus (DM) and is highly associated with devastating outcomes. Hypoxia-inducible factor (HIF), the main transcription factor that regulates cellular responses to hypoxia, plays an important role in reg...

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Detalles Bibliográficos
Autores principales: Jiang, Yumin, Cui, Wen, Zhang, Yiding, Wang, Ting, Zheng, Xuejun, Li, Huangmin, Shang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465800/
https://www.ncbi.nlm.nih.gov/pubmed/37654676
http://dx.doi.org/10.3389/fphys.2023.1195441