Oncolytic virotherapy with chimeric VSV-NDV synergistically supports RIG-I-dependent checkpoint inhibitor immunotherapy

Unraveling the complexities of the tumor microenvironment (TME) and its correlation with responsiveness to immunotherapy has become a main focus in overcoming resistance to such treatments. Targeting tumor-intrinsic retinoic acid-inducible gene-I (RIG-I), a sensor for viral RNA, was shown to transfo...

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Detalles Bibliográficos
Autores principales: Marek, Janina, Hanesch, Lorenz, Krabbe, Teresa, El Khawanky, Nadia, Heidegger, Simon, Altomonte, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465858/
https://www.ncbi.nlm.nih.gov/pubmed/37654972
http://dx.doi.org/10.1016/j.omto.2023.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465858/
https://www.ncbi.nlm.nih.gov/pubmed/37654972
http://dx.doi.org/10.1016/j.omto.2023.08.001

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