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Nano-hesperetin ameliorates 6-hydroxydopamine-induced behavioral deficits and oxidative damage by up-regulating gene expression of antioxidant enzymes

OBJECTIVE: Hesperetin (Hst) has shown several pharmacological effects. The efficacy of Hst is highly restricted in vivo due mainly to poor bioavailability. This investigation was intended to compare the influence of Hst and nano-Hst treatment on 6-hydroxydopamine (6-OHDA)-induced behavioral deficits...

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Detalles Bibliográficos
Autores principales: Hajizadeh Moghaddam, Akbar, Alizadeh, Sara, Nejadi, Monireh, Mokhtari Sangdehi, Seyed Reza, Zare, Mahboobeh, Ranjbar, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465877/
https://www.ncbi.nlm.nih.gov/pubmed/37655004
http://dx.doi.org/10.22038/AJP.2022.21532