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Unique activities of two overlapping PAX6 retinal enhancers

Enhancers play a critical role in development by precisely modulating spatial, temporal, and cell type-specific gene expression. Sequence variants in enhancers have been implicated in diseases; however, establishing the functional consequences of these variants is challenging because of a lack of un...

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Detalles Bibliográficos
Autores principales: Uttley, Kirsty, Papanastasiou, Andrew S, Lahne, Manuela, Brisbane, Jennifer M, MacDonald, Ryan B, Bickmore, Wendy A, Bhatia, Shipra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465922/
https://www.ncbi.nlm.nih.gov/pubmed/37643867
http://dx.doi.org/10.26508/lsa.202302126