Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis

In development of colorectal cancer, mutations in APC are often followed by mutations in oncogene KRAS. The latter changes cellular metabolism and is associated with the Warburg phenomenon. Glucose-regulated protein 78 (Grp78) is an important regulator of the protein-folding machinery, involved in p...

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Detalles Bibliográficos
Autores principales: Spaan, Claudia N, de Boer, Ruben J, Smit, Wouter L, van der Meer, Jonathan HM, van Roest, Manon, Vermeulen, Jacqueline LM, Koelink, Pim J, Becker, Marte AJ, Go, Simei, Silva, Joana, Faller, William J, van den Brink, Gijs R, Muncan, Vanesa, Heijmans, Jarom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465924/
https://www.ncbi.nlm.nih.gov/pubmed/37643866
http://dx.doi.org/10.26508/lsa.202301912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465924/
https://www.ncbi.nlm.nih.gov/pubmed/37643866
http://dx.doi.org/10.26508/lsa.202301912

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