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A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study

A new class of potent liver injury protective compounds, phychetins A−D (1−4) featuring an unique 6/6/5/6/5 pentacyclic framework, were isolated and structurally characterized from a Chinese medicinal plant Phyllanthus franchetianus. Compounds 2−4 are three pairs of enantiomers that were initially o...

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Detalles Bibliográficos
Autores principales: Ji, Kailong, Liu, Wei, Yin, Weihang, Kong, Xiangrong, Xu, Honghong, Lai, Zeng-Wei, Li, Jing-Ya, Yue, Jian-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465957/
https://www.ncbi.nlm.nih.gov/pubmed/37655332
http://dx.doi.org/10.1016/j.apsb.2023.05.001