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Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel

The extremely low bioavailability of oral paclitaxel (PTX) mainly due to the complicated gastrointestinal environment, the obstruction of intestinal mucus layer and epithelium barrier. Thus, it is of great significance to construct a coordinative delivery system which can overcome multiple intestina...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Liu, Wei, Liu, Yanhong, Duan, Hongxia, Chen, Liqing, Zhang, Xintong, Jin, Mingji, Cui, Minhu, Quan, Xiuquan, Pan, Libin, Hu, Jiachun, Gao, Zhonggao, Wang, Yan, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466001/
https://www.ncbi.nlm.nih.gov/pubmed/37655335
http://dx.doi.org/10.1016/j.apsb.2023.05.029