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Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel
The extremely low bioavailability of oral paclitaxel (PTX) mainly due to the complicated gastrointestinal environment, the obstruction of intestinal mucus layer and epithelium barrier. Thus, it is of great significance to construct a coordinative delivery system which can overcome multiple intestina...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466001/ https://www.ncbi.nlm.nih.gov/pubmed/37655335 http://dx.doi.org/10.1016/j.apsb.2023.05.029 |