Cargando…
Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity
Vincristine, a widely used chemotherapeutic agent for treating different cancer, often induces severe peripheral neuropathic pain. A common symptom of vincristine-induced peripheral neuropathic pain is mechanical allodynia and hyperalgesia. However, mechanisms underlying vincristine-induced mechanic...
Autores principales: | Duan, Mingli, Jia, Yurui, Huo, Lifang, Gao, Yiting, Wang, Jia, Zhang, Wei, Jia, Zhanfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466006/ https://www.ncbi.nlm.nih.gov/pubmed/37655331 http://dx.doi.org/10.1016/j.apsb.2023.05.010 |
Ejemplares similares
-
GTP-dependent run-up of Piezo2-type mechanically activated currents in rat dorsal root ganglion neurons
por: Jia, Zhanfeng, et al.
Publicado: (2013) -
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle
por: Han, Yu, et al.
Publicado: (2019) -
PIEZO2 in sensory neurons and urothelial cells coordinates urination
por: Marshall, Kara L., et al.
Publicado: (2020) -
TRPA1 Mediates Mechanical Currents in the Plasma Membrane of Mouse Sensory Neurons
por: Vilceanu, Daniel, et al.
Publicado: (2010) -
Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels
por: Shin, Seung Min, et al.
Publicado: (2023)