Rhodium(i)-catalyzed cascade C(sp(2))–H bond alkylation – amidation of anilines: phosphorus as traceless directing group

We introduce a versatile Rh(i)-catalyzed cascade reaction, combining C(sp(2))–H bond functionalization and amidation between N-arylphosphanamines and acrylates. This innovative approach enables the rapid synthesis of dihydroquinolinone scaffolds, a common heterocycle found in various pharmaceuticals...

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Detalles Bibliográficos
Autores principales: Peng, Marie, Ari, Denis, Roisnel, Thierry, Doucet, Henri, Soulé, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466282/
https://www.ncbi.nlm.nih.gov/pubmed/37655033
http://dx.doi.org/10.1039/d3sc02992a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466282/
https://www.ncbi.nlm.nih.gov/pubmed/37655033
http://dx.doi.org/10.1039/d3sc02992a

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