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Rhodium(i)-catalyzed cascade C(sp(2))–H bond alkylation – amidation of anilines: phosphorus as traceless directing group

We introduce a versatile Rh(i)-catalyzed cascade reaction, combining C(sp(2))–H bond functionalization and amidation between N-arylphosphanamines and acrylates. This innovative approach enables the rapid synthesis of dihydroquinolinone scaffolds, a common heterocycle found in various pharmaceuticals...

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Detalles Bibliográficos
Autores principales:	Peng, Marie, Ari, Denis, Roisnel, Thierry, Doucet, Henri, Soulé, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466282/ https://www.ncbi.nlm.nih.gov/pubmed/37655033 http://dx.doi.org/10.1039/d3sc02992a

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