Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases

Lysosomal exoglycosidases are responsible for processing endocytosed glycans from the non-reducing end to produce the corresponding monosaccharides. Genetic mutations in a particular lysosomal glycosidase may result in accumulation of its particular substrate, which may cause diverse lysosomal stora...

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Detalles Bibliográficos
Autores principales: van der Gracht, Daniël, Rowland, Rhianna J., Roig-Zamboni, Véronique, Ferraz, Maria J., Louwerse, Max, Geurink, Paul P., Aerts, Johannes M. F. G., Sulzenbacher, Gerlind, Davies, Gideon J., Overkleeft, Herman S., Artola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466331/
https://www.ncbi.nlm.nih.gov/pubmed/37655021
http://dx.doi.org/10.1039/d3sc01021j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466331/
https://www.ncbi.nlm.nih.gov/pubmed/37655021
http://dx.doi.org/10.1039/d3sc01021j

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