Building Block-Based Binding Predictions for DNA-Encoded Libraries

[Image: see text] DNA-encoded libraries (DELs) provide the means to make and screen millions of diverse compounds against a target of interest in a single experiment. However, despite producing large volumes of binding data at a relatively low cost, the DEL selection process is susceptible to noise,...

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Detalles Bibliográficos
Autores principales: Zhang, Chris, Pitman, Mary, Dixit, Anjali, Leelananda, Sumudu, Palacci, Henri, Lawler, Meghan, Belyanskaya, Svetlana, Grady, LaShadric, Franklin, Joe, Tilmans, Nicolas, Mobley, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466377/
https://www.ncbi.nlm.nih.gov/pubmed/37578123
http://dx.doi.org/10.1021/acs.jcim.3c00588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466377/
https://www.ncbi.nlm.nih.gov/pubmed/37578123
http://dx.doi.org/10.1021/acs.jcim.3c00588

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