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Biological insights in non-small cell lung cancer

Lung oncogenesis relies on intracellular cysteine to overcome oxidative stress. Several tumor types, including non-small cell lung cancer (NSCLC), upregulate the system x(c)(-) cystine/glutamate antiporter (xCT) through overexpression of the cystine transporter SLC7A11, thus sustaining intracellular...

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Detalles Bibliográficos
Autores principales: Rosell, Rafael, Jain, Anisha, Codony-Servat, Jordi, Jantus-Lewintre, Eloisa, Morrison, Blake, Ginesta, Jordi Barretina, González-Cao, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466437/
https://www.ncbi.nlm.nih.gov/pubmed/37381723
http://dx.doi.org/10.20892/j.issn.2095-3941.2023.0108