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Evaluating Dual-Targeted ECO/siRNA Nanoparticles against an Oncogenic lncRNA for Triple Negative Breast Cancer Therapy with Magnetic Resonance Molecular Imaging

[Image: see text] Differentiation antagonizing noncoding RNA (DANCR) is recognized as an oncogenic long noncoding RNA (lncRNA) overexpressed in triple negative breast cancer (TNBC). We showed in a previous study that RNAi with targeted multifunctional ionizable lipid ECO/siRNA nanoparticles was effe...

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Detalles Bibliográficos
Autores principales: Nicolescu, Calin, Schilb, Andrew, Kim, Jiyoon, Sun, Da, Hall, Ryan, Gao, Songqi, Gilmore, Hannah, Schiemann, William P., Lu, Zheng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nanjing University and American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466452/
https://www.ncbi.nlm.nih.gov/pubmed/37655165
http://dx.doi.org/10.1021/cbmi.3c00011