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MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer

BACKGROUND: MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the surface of natural killer cells (NK cells), B cells, and monocytes. However, the r...

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Detalles Bibliográficos
Autores principales: Wu, Yuliang, Liu, Qi, Xie, Yan, Zhu, Jihui, Zhang, Sai, Ge, Yao, Guo, Jing, Luo, Ning, Huang, Wei, Xu, Runping, Liu, Shupeng, Cheng, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466733/
https://www.ncbi.nlm.nih.gov/pubmed/37644468
http://dx.doi.org/10.1186/s13048-023-01207-0