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Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study
BACKGROUND: Despite the high sensitivity of cerebrospinal fluid (CSF) amyloid beta (Aβ)(42) to detect amyloid pathology, the Aβ(42)/Aβ(40) ratio (amyR) better estimates amyloid load, with higher specificity for Alzheimer’s disease (AD). However, whether Aβ(42) and amyR have different meanings and wh...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466826/ https://www.ncbi.nlm.nih.gov/pubmed/37649105 http://dx.doi.org/10.1186/s13195-023-01291-w |