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Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study

BACKGROUND: Despite the high sensitivity of cerebrospinal fluid (CSF) amyloid beta (Aβ)(42) to detect amyloid pathology, the Aβ(42)/Aβ(40) ratio (amyR) better estimates amyloid load, with higher specificity for Alzheimer’s disease (AD). However, whether Aβ(42) and amyR have different meanings and wh...

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Detalles Bibliográficos
Autores principales: Motta, Caterina, Di Donna, Martina Gaia, Bonomi, Chiara Giuseppina, Assogna, Martina, Chiaravalloti, Agostino, Mercuri, Nicola Biagio, Koch, Giacomo, Martorana, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466826/
https://www.ncbi.nlm.nih.gov/pubmed/37649105
http://dx.doi.org/10.1186/s13195-023-01291-w