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Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway

BACKGROUND: The transferrin receptor (TfR) encoded by TFRC gene is the main cellular iron importer. TfR is highly expressed in many cancers and is expected to be a promising new target for cancer therapy; however, its role in nasopharyngeal carcinoma (NPC) remains unknown. METHODS: The TfR levels we...

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Detalles Bibliográficos
Autores principales: Feng, Guofei, Arima, Yasushi, Midorikawa, Kaoru, Kobayashi, Hatasu, Oikawa, Shinji, Zhao, Weilin, Zhang, Zhe, Takeuchi, Kazuhiko, Murata, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466839/
https://www.ncbi.nlm.nih.gov/pubmed/37644594
http://dx.doi.org/10.1186/s12935-023-02995-7