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Combining bulk and single-cell RNA-sequencing data to develop an NK cell-related prognostic signature for hepatocellular carcinoma based on an integrated machine learning framework

BACKGROUND: The application of molecular targeting therapy and immunotherapy has notably prolonged the survival of patients with hepatocellular carcinoma (HCC). However, multidrug resistance and high molecular heterogeneity of HCC still prevent the further improvement of clinical benefits. Dysfuncti...

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Detalles Bibliográficos
Autores principales: Feng, Qian, Huang, Zhihao, Song, Lei, Wang, Le, Lu, Hongcheng, Wu, Linquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466881/
https://www.ncbi.nlm.nih.gov/pubmed/37649103
http://dx.doi.org/10.1186/s40001-023-01300-6